- Depart Springfield / Branson Regional Airport, drive south on Airport Blvd. from the airport to Highway 266. Turn left and go about one mile to I-44.
- Take I-44 east Travel east on I-44 for 8.8 miles to Exit 82A/US-65 South to Branson.
- Drive South for 35 miles until you reach Forsyth/Reeds Spring Exit (Rt.160).
- Exit and turn left(east) on Rt. 160 and travel 9 miles until you reach the Forsyth city limits sign.
- National Enzyme Company is located 1/2 mile beyond the city limit sign on the right side of the road.